It depends on what you're trying to do. e-commerce is a pretty broad category. If you're just trying to sell a small amount of product, Shopify or Woo are pretty good sites. If you want to host a yourself, I would go with WHMCS.
You mean to create your own e-commerce site?
I'd do it from scratch, but I'm silly that way.
A friend of mine uses Shopify, but I can't really vouch for it myself, because I'm pretty far removed from the e-commerce realm. Take a look, though. He claims it's easy to set up / configure.
@thelonius shopify, but it costs. Squarespace, but it costs less. WordPress + Woocommerce, more complex but free.
I do the latter, when it starts making bank I'm heading for Shopify.
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