This fundamental study looks at the role of Ezrin, a membrane-actin linker that assembles signalling complexes, unveiling a critical endosome–lysosome network essential for #autophagy and cellular #homeostasis.
https://elifesciences.org/articles/98523?utm_source=mastodon&utm_medium=social&utm_campaign=organic

Caspases have well known roles in #apoptosis, but roles in other cellular processes are emerging... This study shows that #caspase -3 & -7 promote cytoprotective #autophagy in response to non-lethal stress by modulating PARP1 activity in #BreastCancer cells #plosbiology https://plos.io/41xfLVm

#Cellular clean-up: Solving the mystery of how cells initiate their recycling process.

#PI3_kinase #VPS15 #autophagy

https://phys.org/news/2025-02-cellular-mystery-cells-recycling.html

Roles of the autophagy gene ATG7 in health and disease

Margrét Helga Ögmundsdóttir talk at #UniversityIceland

The essential mammalian gene, ATG7, has been widely studied in connection with autophagy. 
#cellbiology #autophagy #genetics #evolution #Iceland #atg7 #atg8

https://hi.is/vidburdir/malstofa_lifvisindaseturs_roles_of_the_autophagy_gene_atg7_in_health_and_disease

What is the mechanistic link between the NLRP3 #inflammasome, #autophagy & inflammatory #bowel disease (IBD)? This study shows that VANGL2 reduces #IBD progression by recruiting the ubiquitin ligase MARCH8 to regulate NLRP3 activation via OPTN-mediated autophagy plosbiology https://plos.io/42FTqFO

Fully Funded PhD Position in Cancer Research

Hebrew University of Jerusalem

See the full job description on jobRxiv: https://jobrxiv.org/job/hebrew-university-of-jerusalem-27778-fully-funded-phd-position-in-cancer-research/?feed_id=91606

#autophagy #cancer_biology #cell_death #mitophagy #ScienceJobs #hiring #research
https://jobrxiv.org/job/hebrew-university-of-jerusalem-27778-fully-funded-phd-position-in-cancer-research/?feed_id=91606

Autophagy - Enhance Your Health

https://talknet.substack.com/p/autophagy-level-up-your-health

Postdoctoral Researcher in Plant Molecular Biology and Autophagy

University of Louvain, Louvain-la-Neuve

See the full job description on jobRxiv: https://jobrxiv.org/job/university-of-louvain-louvain-la-neuve-27778-postdoctoral-researcher-in-plant-molecular-biology-and-autophagy/?feed_id=89765

#abiotic_stress #autophagosome #autophagy #bioche...
https://jobrxiv.org/job/university-of-louvain-louvain-la-neuve-27778-postdoctoral-researcher-in-plant-molecular-biology-and-autophagy/?feed_id=89765

Open PhD student position

Hebrew University of Jerusalem

Our lab studies the relationship between metabolism, mitochondrial dysfunction and mitophagy in S. cerevisiae.

See the full job description on jobRxiv: https://jobrxiv.org/job/hebrew-university-of-jerusalem-27778-open-phd-student-position/?feed_id=89240

#autophagy #biochemistry #cell_biology #kinases #mitophagy #phosphorylation #Sc...
https://jobrxiv.org/job/hebrew-university-of-jerusalem-27778-open-phd-student-position/?feed_id=89240

#autophagy is so hot right now! So here’s an update on autophagy disorders

Hormos Salimi Dafsari, et al
https://doi.org/10.1002/jimd.12798

Postdoctoral Researcher in Plant Molecular Biology and Autophagy

University of Louvain, Louvain-la-Neuve

See the full job description on jobRxiv: https://jobrxiv.org/job/university-of-louvain-louvain-la-neuve-27778-postdoctoral-researcher-in-plant-molecular-biology-and-autophagy/?feed_id=88372

#abiotic_stress #autophagosome #autophagy #bioche...
https://jobrxiv.org/job/university-of-louvain-louvain-la-neuve-27778-postdoctoral-researcher-in-plant-molecular-biology-and-autophagy/?feed_id=88372

Postdoctoral Researcher in Plant Molecular Biology and Autophagy

University of Louvain, Louvain-la-Neuve

See the full job description on jobRxiv: https://jobrxiv.org/job/university-of-louvain-louvain-la-neuve-27778-postdoctoral-researcher-in-plant-molecular-biology-and-autophagy/?feed_id=88022

#abiotic_stress #autophagosome #autophagy #bioche...
https://jobrxiv.org/job/university-of-louvain-louvain-la-neuve-27778-postdoctoral-researcher-in-plant-molecular-biology-and-autophagy/?feed_id=88022

Valgerður Jakobína Hjaltalín phd thesis:The role of the key autophagy gene ATG7 in vertebrates

#autophagy #evolution #starvation #metabolism #UniversityIceland

https://lifvisindi.hi.is/doctoral-defence-valgerdur-jakobina-hjaltalin?origin=serp_auto

Including
"A novel region within a conserved domain in ATG7 emerged in vertebrates"

Zhang et al. establish a #molecular link between #autophagy and vacuolar #protein transport--and offer insights into the dual functions of the MON1–CCZ1 complex in #plants.
Read the full paper here! #OpenAccess
https://doi.org/10.1111/jipb.13792
@wileyplantsci
#JIPB #PlantSci #botany

Open PhD student position

Hebrew University of Jerusalem

Our lab studies the relationship between metabolism, mitochondrial dysfunction and mitophagy in S. cerevisiae.

See the full job description on jobRxiv: https://jobrxiv.org/job/hebrew-university-of-jerusalem-27778-open-phd-student-position/?feed_id=86297

#autophagy #biochemistry #cell_biology #kinases #mitophagy #phosphorylation #Sc...
https://jobrxiv.org/job/hebrew-university-of-jerusalem-27778-open-phd-student-position/?feed_id=86297

"Our study demonstrates a unique role for MANF in autophagy and lysosome function, critical processes for clearing toxic proteins. In the animal model Caenorhabditis elegans, overexpressing MANF extended lifespan, reduced protein clumps, and conferred protection on neurons. These roles of MANF are mediated by the HLH-30/TFEB, a master regulator of lysosome function"

https://www.pnas.org/doi/10.1073/pnas.2403906121

Postdoctoral Fellow in Cell Biology, Biochemistry or Proteomics (New York).

Sloan Kettering Institute

Come join us as a Postdoctoral Fellow to study #Ubiquitin, #Autophagy, #Biochemistry, and #Proteomics at the Sloan Kettering Institute in New York.

See the full job description on jobRxiv: https://jobrxiv.org/job/sloan-kettering-institute-27778-pos...
https://jobrxiv.org/job/sloan-kettering-institute-27778-postdoctoral-fellow-in-cell-biology-biochemistry-or-proteomics-new-york/?feed_id=83899

Postdoctoral Fellow in Cell Biology, Biochemistry or Proteomics (New York).

Sloan Kettering Institute

Come join us as a Postdoctoral Fellow to study #Ubiquitin, #Autophagy, #Biochemistry, and #Proteomics at the Sloan Kettering Institute in New York.

See the full job description on jobRxiv: https://jobrxiv.org/job/sloan-kettering-institute-27778-pos...
https://jobrxiv.org/job/sloan-kettering-institute-27778-postdoctoral-fellow-in-cell-biology-biochemistry-or-proteomics-new-york/?feed_id=81143

Nein! Doch! Ooooh!!! #KI is dying. #peakAI is coming in these days, these years. #autophagy #MadAIsyndrom Brace yourself! #AIWinter is coming.
#toldyouso for years.

https://www.deutschlandfunk.de/ki-kollaps-daten-sprachmodelle-training-dlf-d0b03f04-100.html

#Drought stress limits #plant #growth and #development, but #autophagy of misfolded #proteins can help alleviate drought-related damage. Here, Xiang et al. explore the role of autophagy receptor #ZmNBR1 in drought tolerance.
https://doi.org/10.1111/jipb.13662
@wileyplantsci
#PlantSci #maize #botany