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Hacker NewsColossal Cave Adventure (1976)<a href="https://github.com/wh0am1-dev/adventure" rel="nofollow noopener" translate="no" target="_blank">https://github.com/wh0am1-dev/adventure</a><a href="https://mastodon.social/tags/HackerNews" class="mention hashtag" rel="nofollow noopener" target="_blank">#HackerNews</a> <a href="https://mastodon.social/tags/Colossal" class="mention hashtag" rel="nofollow noopener" target="_blank">#Colossal</a> <a href="https://mastodon.social/tags/Cave" class="mention hashtag" rel="nofollow noopener" target="_blank">#Cave</a> <a href="https://mastodon.social/tags/Adventure" class="mention hashtag" rel="nofollow noopener" target="_blank">#Adventure</a> #1976 <a href="https://mastodon.social/tags/retro" class="mention hashtag" rel="nofollow noopener" target="_blank">#retro</a> <a href="https://mastodon.social/tags/gaming" class="mention hashtag" rel="nofollow noopener" target="_blank">#gaming</a> <a href="https://mastodon.social/tags/text" class="mention hashtag" rel="nofollow noopener" target="_blank">#text</a> <a href="https://mastodon.social/tags/adventure" class="mention hashtag" rel="nofollow noopener" target="_blank">#adventure</a> <a href="https://mastodon.social/tags/gaming" class="mention hashtag" rel="nofollow noopener" target="_blank">#gaming</a> <a href="https://mastodon.social/tags/history" class="mention hashtag" rel="nofollow noopener" target="_blank">#history</a> <a href="https://mastodon.social/tags/interactive" class="mention hashtag" rel="nofollow noopener" target="_blank">#interactive</a> <a href="https://mastodon.social/tags/fiction" class="mention hashtag" rel="nofollow noopener" target="_blank">#fiction</a>

Knowledge ZoneHow to <a href="https://mstdn.social/tags/Think" class="mention hashtag" rel="nofollow noopener" target="_blank">#Think</a> About Your <a href="https://mstdn.social/tags/Career" class="mention hashtag" rel="nofollow noopener" target="_blank">#Career</a> : MediumUnravelling the <a href="https://mstdn.social/tags/Secrets" class="mention hashtag" rel="nofollow noopener" target="_blank">#Secrets</a> of the <a href="https://mstdn.social/tags/VagusNerve" class="mention hashtag" rel="nofollow noopener" target="_blank">#VagusNerve</a> will <a href="https://mstdn.social/tags/Revolutionise" class="mention hashtag" rel="nofollow noopener" target="_blank">#Revolutionise</a> <a href="https://mstdn.social/tags/Medicine" class="mention hashtag" rel="nofollow noopener" target="_blank">#Medicine</a> : New Sci<a href="https://mstdn.social/tags/Colossal" class="mention hashtag" rel="nofollow noopener" target="_blank">#Colossal</a> <a href="https://mstdn.social/tags/Squid" class="mention hashtag" rel="nofollow noopener" target="_blank">#Squid</a> filmed in <a href="https://mstdn.social/tags/Ocean" class="mention hashtag" rel="nofollow noopener" target="_blank">#Ocean</a> for the first time : BBCCheck our latest <a href="https://mstdn.social/tags/KnowledgeLinks" class="mention hashtag" rel="nofollow noopener" target="_blank">#KnowledgeLinks</a><a href="https://knowledgezone.co.in/resources/bookmarks" rel="nofollow noopener" translate="no" target="_blank">https://knowledgezone.co.in/resources/bookmarks</a>

Jenny LepiesSkurriler geht es fast nicht mehr - Nicht nur das Wollhaarmammut zurückbringen wollen, sondern nun auch Patente auf die (vermeintlich) wiederbelebten Tiere beantragen. 🙄 Ich stelle mir den Moment ein bisschen lustig vor, als der US-Redakteur den CEO fragt, ob sie beabsichtigen, einen Merchandise-Laden zu eröffnen. <a href="https://mstdn.social/tags/Mammut" class="mention hashtag" rel="nofollow noopener" target="_blank">#Mammut</a> <a href="https://mstdn.social/tags/Colossal" class="mention hashtag" rel="nofollow noopener" target="_blank">#Colossal</a> <a href="https://mstdn.social/tags/colossal_biosciences" class="mention hashtag" rel="nofollow noopener" target="_blank">#colossal_biosciences</a> <a href="https://mstdn.social/tags/Biotechnologie" class="mention hashtag" rel="nofollow noopener" target="_blank">#Biotechnologie</a> <a href="https://t3n.de/news/patent-auf-ausgestorbenes-mammut-so-will-sich-das-wiederbelebungs-startup-das-markenrecht-sichern-1684190/" rel="nofollow noopener" translate="no" target="_blank">https://t3n.de/news/patent-auf-ausgestorbenes-mammut-so-will-sich-das-wiederbelebungs-startup-das-markenrecht-sichern-1684190/</a>

Moreno Colaiacovo"Fino alla settimana scorsa questa vignetta era solo un piccolo colpo di genio umoristico, simbolo della distanza siderale tra chi è ricco e chi no. Ora però, con i falsi <a href="https://sayansi.social/tags/metalupi" class="mention hashtag" rel="nofollow noopener" target="_blank">#metalupi</a> di <a href="https://sayansi.social/tags/Colossal" class="mention hashtag" rel="nofollow noopener" target="_blank">#Colossal</a>, potremmo aver visto i primissimi passi di questo scenario. Un giorno un bambino ricco potrebbe davvero ricevere un <a href="https://sayansi.social/tags/Pikachu" class="mention hashtag" rel="nofollow noopener" target="_blank">#Pikachu</a> come animaletto da compagnia."<a href="https://demonsdancealone.substack.com/p/pikachu-nella-foresta-dei-metalupi" rel="nofollow noopener" translate="no" target="_blank">https://demonsdancealone.substack.com/p/pikachu-nella-foresta-dei-metalupi</a>

ONC NewsHistoric Marine Discovery: Elusive Colossal Squid Filmed Alive in Deep Ocean <a href="https://oncnnews.blogspot.com/2025/04/historic-marine-discovery-elusive.html" rel="nofollow noopener" translate="no" target="_blank">https://oncnnews.blogspot.com/2025/04/historic-marine-discovery-elusive.html</a> <a href="https://mastodon.social/tags/colossal" class="mention hashtag" rel="nofollow noopener" target="_blank">#colossal</a> <a href="https://mastodon.social/tags/colossal" class="mention hashtag" rel="nofollow noopener" target="_blank">#colossal</a> <a href="https://mastodon.social/tags/Squid" class="mention hashtag" rel="nofollow noopener" target="_blank">#Squid</a> <a href="https://mastodon.social/tags/Colossal" class="mention hashtag" rel="nofollow noopener" target="_blank">#Colossal</a> <a href="https://mastodon.social/tags/ColossalSquid" class="mention hashtag" rel="nofollow noopener" target="_blank">#ColossalSquid</a> <a href="https://mastodon.social/tags/Squid" class="mention hashtag" rel="nofollow noopener" target="_blank">#Squid</a> <a href="https://mastodon.social/tags/Colossal" class="mention hashtag" rel="nofollow noopener" target="_blank">#Colossal</a> <a href="https://mastodon.social/tags/ColossalSquid" class="mention hashtag" rel="nofollow noopener" target="_blank">#ColossalSquid</a> <a href="https://mastodon.social/tags/news" class="mention hashtag" rel="nofollow noopener" target="_blank">#news</a> <a href="https://mastodon.social/tags/USA" class="mention hashtag" rel="nofollow noopener" target="_blank">#USA</a> <a href="https://mastodon.social/tags/BreakingNews" class="mention hashtag" rel="nofollow noopener" target="_blank">#BreakingNews</a>

Faraiwe<a href="https://mstdn.social/tags/Colossal" class="mention hashtag" rel="nofollow noopener" target="_blank">#Colossal</a> <a href="https://mstdn.social/tags/DireWolf" class="mention hashtag" rel="nofollow noopener" target="_blank">#DireWolf</a>

Xamanismo Coletivo<a href="https://hachyderm.io/tags/deExtinction" class="mention hashtag" rel="nofollow noopener" target="_blank">#deExtinction</a>: "The American company <a href="https://hachyderm.io/tags/Colossal" class="mention hashtag" rel="nofollow noopener" target="_blank">#Colossal</a> changed only 14 genes to produce its cute "<a href="https://hachyderm.io/tags/direwolf" class="mention hashtag" rel="nofollow noopener" target="_blank">#direwolf</a>" puppies. Curiously, all 14 are genes with effects on the appearance of animals, being linked to the colour, thickness and length of the fur and the size of the animals.Is <a href="https://hachyderm.io/tags/resurrecting" class="mention hashtag" rel="nofollow noopener" target="_blank">#resurrecting</a> a species now just <a href="https://hachyderm.io/tags/cosplaying" class="mention hashtag" rel="nofollow noopener" target="_blank">#cosplaying</a> an extinct animal with a current species? To top it off, George R.R. Martin himself - yes, the author of <a href="https://hachyderm.io/tags/GameofThrones" class="mention hashtag" rel="nofollow noopener" target="_blank">#GameofThrones</a> - signs the scientific article as well. And he is an investor in the company. He compared the feat to a form of "magic". Only if it's to magically fatten his bank account even more."<a href="https://www1.folha.uol.com.br/colunas/reinaldojoselopes/2025/04/notas-sobre-a-pantomima-do-lobo-gigante.shtml" rel="nofollow noopener" translate="no" target="_blank">https://www1.folha.uol.com.br/colunas/reinaldojoselopes/2025/04/notas-sobre-a-pantomima-do-lobo-gigante.shtml</a>

ansuz / ऐरनI've found all the discourse about Colossal Biosciences "Dire wolf" announcement very annoying, because it seems like a lot of the exchanges have been between a bunch of pedantic nerds and what is probbaly Colossal's marketing/public-outreach department. Honestly, I think both camps are wrong in their own way, and it's turning into more of a shouting match than anything.The core problem is that there are many different definitions of species, none of which are perfect, and almost all of them cease to be meaningful in cases where horizontal gene transfer occurs.<a href="https://social.cryptography.dog/tags/direWolf" class="mention hashtag" rel="nofollow noopener" target="_blank">#direWolf</a> <a href="https://social.cryptography.dog/tags/colossal" class="mention hashtag" rel="nofollow noopener" target="_blank">#colossal</a> <a href="https://social.cryptography.dog/tags/biology" class="mention hashtag" rel="nofollow noopener" target="_blank">#biology</a>

Jenny Lepies"Es ist kein Schattenwolf" - "Es ist ein Schattenwolf": Was klingt wie ein Loriot-Sketch will harte Wissenschaft sein. <a href="https://mstdn.social/tags/Wolf" class="mention hashtag" rel="nofollow noopener" target="_blank">#Wolf</a> <a href="https://mstdn.social/tags/Colossal" class="mention hashtag" rel="nofollow noopener" target="_blank">#Colossal</a> <a href="https://mstdn.social/tags/Biotechnologie" class="mention hashtag" rel="nofollow noopener" target="_blank">#Biotechnologie</a> <a href="https://mstdn.social/tags/Biologie" class="mention hashtag" rel="nofollow noopener" target="_blank">#Biologie</a> <a href="https://t3n.de/news/ausgestorbener-schattenwolf-oder-grauwolf-warum-an-20-genveraenderungen-ein-streit-entbrennt-1682454/" rel="nofollow noopener" translate="no" target="_blank">https://t3n.de/news/ausgestorbener-schattenwolf-oder-grauwolf-warum-an-20-genveraenderungen-ein-streit-entbrennt-1682454/</a>

Moreno Colaiacovo"Se l’approccio di <a href="https://sayansi.social/tags/Colossal" class="mention hashtag" rel="nofollow noopener" target="_blank">#Colossal</a> continuerà ad essere quello che si direbbe sia stato con l’enocione, allora gli eventuali “mammut del futuro” non saranno altro che elefanti indiani modificati per avere, che so io, una pelliccia piuttosto folta, o magari, per essere capaci di resistere a temperature basse."<a href="https://www.queryonline.it/2025/04/08/jurassic-wolves-abbiamo-davvero-de-estinto-i-metalupi-intervista-a-massimo-sandal/" rel="nofollow noopener" translate="no" target="_blank">https://www.queryonline.it/2025/04/08/jurassic-wolves-abbiamo-davvero-de-estinto-i-metalupi-intervista-a-massimo-sandal/</a>

Jack Liddle | JFit was my impression that thick white fur was more prevalent in arctic wolves, as it is obviously advantageous in such an environment. dire wolves lived in a temperate, or even rather warm region, so pale fur would certainly not be my first thought when it came to the coat colouration of dire wolves, anyone else find this suspect, especially since colossal evidently worked pretty hard to make them this colour?<a href="https://sauropods.win/tags/wolf" class="mention hashtag" rel="nofollow noopener" target="_blank">#wolf</a> <a href="https://sauropods.win/tags/colossal" class="mention hashtag" rel="nofollow noopener" target="_blank">#colossal</a> <a href="https://sauropods.win/tags/direwolves" class="mention hashtag" rel="nofollow noopener" target="_blank">#direwolves</a>

Jack Liddle | JFmy thing on the <a href="https://sauropods.win/tags/colossal" class="mention hashtag" rel="nofollow noopener" target="_blank">#colossal</a> <a href="https://sauropods.win/tags/direwolves" class="mention hashtag" rel="nofollow noopener" target="_blank">#direwolves</a> WHAT DOES THIS MEAN FOR <a href="https://sauropods.win/tags/PALEOART" class="mention hashtag" rel="nofollow noopener" target="_blank">#PALEOART</a>? obviously until that dire wolf genome is released to the public (something colossal said they would do) and is analyzed by proper scientists, and assuming what they find matches with what colossal has said (which certainly isn't a guarantee) should dire wolves be depicted in a way similar to the colossal specimens- mostly the thick white fur (more on that)<a href="https://sauropods.win/tags/wolf" class="mention hashtag" rel="nofollow noopener" target="_blank">#wolf</a> <a href="https://sauropods.win/tags/paleontology" class="mention hashtag" rel="nofollow noopener" target="_blank">#paleontology</a> <a href="https://sauropods.win/tags/dinosaurs" class="mention hashtag" rel="nofollow noopener" target="_blank">#dinosaurs</a>

HoldMyType<a href="https://mathstodon.xyz/tags/Colossal" class="mention hashtag" rel="nofollow noopener" target="_blank">#Colossal</a> <a href="https://mathstodon.xyz/tags/Biosciences" class="mention hashtag" rel="nofollow noopener" target="_blank">#Biosciences</a> announced the world’s first “de-extinction” on Monday, revealing it had created three “dire wolves” by editing modern gray wolf DNA with <a href="https://mathstodon.xyz/tags/DNA" class="mention hashtag" rel="nofollow noopener" target="_blank">#DNA</a> from the extinct wolves<a href="https://www.businesswire.com/news/home/20250407444322/en/Colossal-Announces-Worlds-First-De-Extinction-Birth-of-Dire-Wolves" rel="nofollow noopener" translate="no" target="_blank">https://www.businesswire.com/news/home/20250407444322/en/Colossal-Announces-Worlds-First-De-Extinction-Birth-of-Dire-Wolves</a>

BlogorgonopsidNe, pravlk obrovský není zpátky. Vyhynutí trvá navždy. To, co Colossal Biosciences vytvořily, jsou geneticky modifikovaní vlci druhu Canis lupus. Je smutné vidět, jak je veřejnosti bezostyšně lháno tolika médii.<a href="https://mastodon.social/tags/direwolf" class="mention hashtag" rel="nofollow noopener" target="_blank">#direwolf</a> <a href="https://mastodon.social/tags/canislupus" class="mention hashtag" rel="nofollow noopener" target="_blank">#canislupus</a> <a href="https://mastodon.social/tags/wolf" class="mention hashtag" rel="nofollow noopener" target="_blank">#wolf</a> <a href="https://mastodon.social/tags/genetics" class="mention hashtag" rel="nofollow noopener" target="_blank">#genetics</a> <a href="https://mastodon.social/tags/paleogenetics" class="mention hashtag" rel="nofollow noopener" target="_blank">#paleogenetics</a> <a href="https://mastodon.social/tags/ancientdna" class="mention hashtag" rel="nofollow noopener" target="_blank">#ancientdna</a> <a href="https://mastodon.social/tags/dna" class="mention hashtag" rel="nofollow noopener" target="_blank">#dna</a> <a href="https://mastodon.social/tags/cloning" class="mention hashtag" rel="nofollow noopener" target="_blank">#cloning</a> <a href="https://mastodon.social/tags/prehistoric" class="mention hashtag" rel="nofollow noopener" target="_blank">#prehistoric</a> <a href="https://mastodon.social/tags/animals" class="mention hashtag" rel="nofollow noopener" target="_blank">#animals</a> <a href="https://mastodon.social/tags/extinction" class="mention hashtag" rel="nofollow noopener" target="_blank">#extinction</a> <a href="https://mastodon.social/tags/deextinction" class="mention hashtag" rel="nofollow noopener" target="_blank">#deextinction</a> <a href="https://mastodon.social/tags/media" class="mention hashtag" rel="nofollow noopener" target="_blank">#media</a> <a href="https://mastodon.social/tags/colossal" class="mention hashtag" rel="nofollow noopener" target="_blank">#colossal</a> <a href="https://mastodon.social/tags/biosciences" class="mention hashtag" rel="nofollow noopener" target="_blank">#biosciences</a> <a href="https://blogorgonopsid.blogspot.com/2025/04/pravlk-obrovsky-je-zpet-kdepak-jde-jen.html" rel="nofollow noopener" translate="no" target="_blank">https://blogorgonopsid.blogspot.com/2025/04/pravlk-obrovsky-je-zpet-kdepak-jde-jen.html</a>

BlogorgonopsidNo, the dire wolf isn't back. Extinction is forever. What Colossal Biosciences created are genetically modified wolves of the species Canis lupus. It's sad to see the public unashamedly lied to by so many media.<a href="https://mastodon.social/tags/direwolf" class="mention hashtag" rel="nofollow noopener" target="_blank">#direwolf</a> <a href="https://mastodon.social/tags/canislupus" class="mention hashtag" rel="nofollow noopener" target="_blank">#canislupus</a> <a href="https://mastodon.social/tags/wolf" class="mention hashtag" rel="nofollow noopener" target="_blank">#wolf</a> <a href="https://mastodon.social/tags/genetics" class="mention hashtag" rel="nofollow noopener" target="_blank">#genetics</a> <a href="https://mastodon.social/tags/paleogenetics" class="mention hashtag" rel="nofollow noopener" target="_blank">#paleogenetics</a> <a href="https://mastodon.social/tags/ancientdna" class="mention hashtag" rel="nofollow noopener" target="_blank">#ancientdna</a> <a href="https://mastodon.social/tags/dna" class="mention hashtag" rel="nofollow noopener" target="_blank">#dna</a> <a href="https://mastodon.social/tags/cloning" class="mention hashtag" rel="nofollow noopener" target="_blank">#cloning</a> <a href="https://mastodon.social/tags/prehistoric" class="mention hashtag" rel="nofollow noopener" target="_blank">#prehistoric</a> <a href="https://mastodon.social/tags/animals" class="mention hashtag" rel="nofollow noopener" target="_blank">#animals</a> <a href="https://mastodon.social/tags/extinction" class="mention hashtag" rel="nofollow noopener" target="_blank">#extinction</a> <a href="https://mastodon.social/tags/deextinction" class="mention hashtag" rel="nofollow noopener" target="_blank">#deextinction</a> <a href="https://mastodon.social/tags/media" class="mention hashtag" rel="nofollow noopener" target="_blank">#media</a> <a href="https://mastodon.social/tags/colossal" class="mention hashtag" rel="nofollow noopener" target="_blank">#colossal</a> <a href="https://mastodon.social/tags/biosciences" class="mention hashtag" rel="nofollow noopener" target="_blank">#biosciences</a> <a href="https://blogorgonopsid.blogspot.com/2025/04/pravlk-obrovsky-je-zpet-kdepak-jde-jen.html" rel="nofollow noopener" translate="no" target="_blank">https://blogorgonopsid.blogspot.com/2025/04/pravlk-obrovsky-je-zpet-kdepak-jde-jen.html</a>

Petra van Cronenburg“This is a designer dog. This is a genetically modified gray wolf,” says Jacquelyn Gill, a paleoecologist at the University of Maine, who has worked with Shapiro in the past but was not involved in this project. “I have more than 14 Neandertal genes in me, and we wouldn’t call me a Neandertal.” <a href="https://www.scientificamerican.com/article/the-dire-wolf-isnt-back-but-heres-what-de-extinction-tech-can-actually-do/" target="_blank" rel="nofollow noopener" translate="no">https://www.scientificamerican.com/article/the-dire-wolf-isnt-back-but-heres-what-de-extinction-tech-can-actually-do/</a> by @andreatweather.bsky.social‬<a href="https://mastodon.online/tags/deextinction" class="mention hashtag" rel="tag">#deextinction</a> <a href="https://mastodon.online/tags/DireWolf" class="mention hashtag" rel="tag">#DireWolf</a> <a href="https://mastodon.online/tags/Colossal" class="mention hashtag" rel="tag">#Colossal</a> <a href="https://mastodon.online/tags/genetics" class="mention hashtag" rel="tag">#genetics</a>

J. NewtonThis whole Dire <a href="https://ecoevo.social/tags/Wolf" class="mention hashtag" rel="nofollow noopener" target="_blank">#Wolf</a> from <a href="https://ecoevo.social/tags/Colossal" class="mention hashtag" rel="nofollow noopener" target="_blank">#Colossal</a> <a href="https://ecoevo.social/tags/BioScience" class="mention hashtag" rel="nofollow noopener" target="_blank">#BioScience</a> story is like the Ship of <a href="https://ecoevo.social/tags/Theseus" class="mention hashtag" rel="nofollow noopener" target="_blank">#Theseus</a>, except instead of slowly swapping out bits of the original ship, they took a completely different ship, looked at a poorly drawn picture of the Ship of Theseus, changed twenty planks on the deck in a way to make it look like the picture...and then said 'HEY I JUST BUILT THE SHIP OF THESEUS!'.

Rod2ik 🇪🇺 🇨🇵 🇪🇸 🇺🇦 🇨🇦 🇩🇰 🇬🇱La empresa <a href="https://mastodon.social/tags/Colossal" class="mention hashtag" rel="nofollow noopener" target="_blank">#Colossal</a>, que creó los ratones lanudos anuncia la “ <a href="https://mastodon.social/tags/desextinci%C3%B3n" class="mention hashtag" rel="nofollow noopener" target="_blank">#desextinción</a> ” del <a href="https://mastodon.social/tags/lobo" class="mention hashtag" rel="nofollow noopener" target="_blank">#lobo</a> <a href="https://mastodon.social/tags/gigante" class="mention hashtag" rel="nofollow noopener" target="_blank">#gigante</a><a href="https://elpais.com/ciencia/2025-04-07/la-empresa-que-creo-los-ratones-lanudos-anuncia-la-desextincion-del-lobo-gigante.html" rel="nofollow noopener" translate="no" target="_blank">https://elpais.com/ciencia/2025-04-07/la-empresa-que-creo-los-ratones-lanudos-anuncia-la-desextincion-del-lobo-gigante.html</a>

Beer Mat MoviesNew release review: Death of a Unicorn <a href="https://mastodonapp.uk/tags/Colossal" class="mention hashtag" rel="nofollow noopener" target="_blank">#Colossal</a> <a href="https://mastodonapp.uk/tags/Cinemastodon" class="mention hashtag" rel="nofollow noopener" target="_blank">#Cinemastodon</a>

DavidWhat’s next? Cloning dinosaurs with blood from a preserved mosquito? De-extinction is amazing, but this also opens possibilities of creating species that never existed. (Looking at you, mockingjay) <a href="https://mastodon.social/tags/science" class="mention hashtag" rel="nofollow noopener" target="_blank">#science</a> <a href="https://mastodon.social/tags/colossal" class="mention hashtag" rel="nofollow noopener" target="_blank">#colossal</a> <a href="https://mastodon.social/tags/mammoth" class="mention hashtag" rel="nofollow noopener" target="_blank">#mammoth</a><a href="https://apnews.com/article/colossal-biosciences-woolly-mammoth-b381f6f48eeed0828535cf9604263140" rel="nofollow noopener" translate="no" target="_blank">https://apnews.com/article/colossal-biosciences-woolly-mammoth-b381f6f48eeed0828535cf9604263140</a>

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