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#FOAMcc

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🕊️ PEACE Pediatric Extracorporeal Membrane Oxygenation Anticoagulation CollaborativE Consensus Conference
⚙️ influence of #ECLS circuit & components
💉 anticoagulant medications
🎯 monitoring & targets
🧪 monitoring & replacement of AT, fibrinogen, vWF
💉 antifibrinolytic & adjunct hemostatic agents
🔪 perioperative period
🩸 bleeding & thrombotic complications
🔍 priorities for clinical Research
#FOAMcc #FOAMecmo #PedsICU
Summary 🔓 bit.ly/3RU7l5c
& special issue 🔓 bit.ly/3XVOqL7

Selective digestive tract decontamination to prevent nosocomial infections in #ICU
🧭 practical guidance
♟️comprehensive implementation strategy
🔗 multidisciplinary team: substantial group effort required!
Pharmacy & microbiology support essential for SDD, to be integrated in hospital Antimicrobial Stewardship Program and Infection Prevention policy. To be effective, meticulous execution of the full SDD protocol + bedside follow up required for every pr
#FOAMcc on @ICM
🔓 rdcu.be/dL87U

Investigating in #sepsis??
🪡 tailoring treatment to individual needs
⏱️ temporal dynamics of intervention
🔎 population selection challenges
🚧 choose appropriate endpoints
🎨 considerations on design
Editorial free to read #FOAMcc on @ICM
🔓 rdcu.be/dL22c

Refers to 🇫🇷🇪🇸 stepped wedge, cluster randomized trial on impact of implementing 1-h bundle in patients with suspected sepsis in ED: not associated with a significant change in in-hospital mortality.
🔓 rdcu.be/dL27N

Gut microbiome?? Organ implicated in both health and disease... What happens in critical illness?
🧫 intestinal microbiome in #ICU: dysbiosis as potential therapeutic target?? Early & profound disruption with loss of commensals/overgrowth of potential pathogens may occur! These derangements may be associated with acute/chronic organ dysfunction + adverse outcome
⛑️ protective/ecological restorative strategies
Free to read #FOAMcc on Intensive Care Medicine
🔓 rdcu.be/dLuHN

Consumptive coagulopathy during #ECLS
🔎 close monitoring & follow up pivotal during the #ECMO run
⛔️ giving platelets/clotting factors to fix numbers often worsens underlying process
🩸 low doses of anticoagulants may protect both circuit (vs thrombotic complications) & patient (vs bleeding & thrombosis)
⛔️ bleeding complications should NOT always prompt complete cessation of UFH
Detailed underlying pathophysiological process & physiological rationale free to read #FOAMcc
🔓 rdcu.be/dLmXO

🚀 Extended reality in #ICU: ready for take-off?? Here translation of NASA Technology Readiness Levels into clinically applicable scale for XR research + identification of maturity of all recent XR-related critical care studies to determine its applicability.
XR increasingly important tool but small minority of clinically implemented projects identified, highlighting a gap to be bridged to move from testing to structured clinical application.
Free to read #FOAMcc on @ICM
🔓 rdcu.be/dKSPm

📢 June issue of Intensive Care Medicine is now available!!
💦 European Society of Intensive Care Medicine (ESICM) fluid therapy guidelines
🗺️ critical care in LMICs
🩸emergency chemotherapy for hematological patients in #ICU
🫘 #RRT in PedsICU
🧫 #sepsis & bloodstream infection
🫁 proning in #ECMO
🫁 Pes
🫀 #ECLS in cardiogenic shock
🧠 neuromonitoring
& more! Full texts free to read #FOAMcc if you follow the links we share in our social media posts... enjoy!
📎 bit.ly/ICMJun2024

🫘Optimal time to stop continuous renal replacement therapy in children? Decision based on anticipated pathophysiology, underlying diagnoses, fluid balance & recovery of residual renal function (with increasing UO easily available sign, to date). Less CRRT may be more, but right time to cease still open question.
🔓rdcu.be/dKiC7

🫘 Refers to analysis on #CRRT in critically ill children & young adults.
#PedsICU #FOAMcc on @ICM
🔓 rdcu.be/dAs4w

What is happening in this 44-year-old man on VA #ECMO??
🚨 #ECPR after 30 min of refractory cardiac arrest post-myocardial infarction
🫀 recovered native cardiac activity but severe postresuscitation vasoplegia leading to important fluid filling to maintain #extracorporeal blood flow
🖥️ TEE showed right atrial collapse
…. cardiac tamponade?? Collapse reversed within seconds during a transient reduction in EBF
Free to read #FOAMcc #FOAMecmo on @ICM
🔓 rdcu.be/dJW8S

Replicating Spanish 🇪🇸 donor transplant coordination model led by intensivists to increase OD rates in other regions, including LMICS?? Here implementation in Santa Catarina, a Southern Brazilian 🇧🇷 state, resulting in 48.9 pmp deceased donor rates in 2023 ( = approaching Spanish), even without DCD program: This organization might provide more persons the opportunity of donating their organs after death + increase transplant options for patients in need
#FOAMcc on @ICM
🔓 rdcu.be/dJErS

🧫 Outcome of hospital-acquired bloodstream infection?? Not only a matter of bacteria & hosts... several aspects of healthcare organization may have clinical implications! Editorial
🔓 rdcu.be/dJymM

🧫 Refers to analysis on data on hospital-acquired BSI from EUROBACT-2 study highlighting that centre/country factors should be targeted to improve management strategies and outcome of HABSI in #ICU.
🔓 rdcu.be/dJyqE

All free to read #FOAMcc on Intensive Care Medicine

Broad use of processed EEG: ready for prime time??
🧠 anesthesia & sedation monitoring
🔮 future applications
detection of seizure
detection of cerebral hypoperfusion
closed‑loop anesthesia delivery systems
⚠️ limitations
PEEG monitoring systems widely available, easy to apply (but training required to avoid misinterpretation), relatively inexpensive & increasingly used outside OR, with potential for #ICU use.
Free to read #FOAMcc on @ICM
🔓 rdcu.be/dJpvI

Norepinephrine dose reporting? No reason to delay standardization!
💉NE dose has known prognostic implications: dose reporting heterogeneity could bias perception of severity & prognosis, with the risk of triggering early, delayed, inadequate decisions
💉 absolute gap of NE base equivalence wide among different saltbased dose preparation/labeling
Free to read #FOAMcc
🔓 rdcu.be/dISUF

In reply to
🔓 rdcu.be/dISSr

💉 All refer to editorial focusing on NE
🔓 rdcu.be/dGazg