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A quotation from Jane Austen

I would recommend to her and Mr. D. the simple regimen of separate rooms.

Jane Austen (1775-1817) English author
Letter (1817-02-20) to Fanny Austen-Knight

On Fanny's aunt, Mrs. Sophia Deedes, having birthed an eighteenth child.

Sourcing, notes: wist.info/austen-jane/75699/

WIST Quotations · Letter (1817-02-20) to Fanny Austen-Knight - Austen, Jane | WIST QuotationsI would recommend to her and Mr. D. the simple regimen of separate rooms. On Fanny's aunt, Mrs. Sophia Deedes, having birthed an eighteenth child.

Så er årets første frivilligmøde afsluttet!

I dag var første møde i forbindelse med den lille ny OFFSpring festival vi afholder i april.

Det bliver spændende.

Det er så en markant mindre frivilliggruppe end på OFF. "Kun" 45 mod de ~130 vi er i august. Det er længe siden vi har været så få til OFF.

Det lugter lidt af at det bliver 10 spændende dage, omend der stadig er meget der er uafklaret, så er de overordnede rammer ved at være på plads.

Entorno y estilo de vida paterno y efecto en la descendencia a través de efectos epigenéticos. Una revisión recién publicada en JARG: https://buff.ly/4ghfYAq #bianorbiotech #JARG #epigenetics #MaleFactor #Offspring #environment

Multifaceted paternal exposure...

SpringerLinkMultifaceted paternal exposures before conception and their epigenetic impact on offspring - Journal of Assisted Reproduction and GeneticsAs scientific research progresses, there is an increasing understanding of the importance of paternal epigenetics in influencing the health and developmental path of offspring. Prior to conception, the environmental exposures and lifestyle choices of fathers can significantly influence the epigenetic state of sperm, including DNA methylation and histone changes, among other factors. These alterations in epigenetic patterns have the potential for transgenerational transmission potential and may exert profound effects on the biological characteristics of descendants. Paternal epigenetic changes not only affect the regulation of gene expression patterns in offspring but also increase the risk to certain diseases. It is crucial to comprehend the conditions that fathers are exposed to before conception and the potential outcomes of these conditions. This understanding is essential for assessing personal reproductive decisions and anticipating health risks for future generations. This review article systematically summarizes and analyzes current research findings regarding how paternal pre-pregnancy exposures influence offspring as well as elucidates underlying mechanisms, aiming to provide a comprehensive perspective for an enhanced understanding of the impact that paternal factors have on offspring health.