I felt the need to thoroughly read — and comment on — the rightly hyped recent publication in Nature Medicine:
Tessier, AJ., Wang, F., Korat, A.A. et al.
Optimal dietary patterns for healthy ageing
https://doi.org/10.1038/s41591-025-03570-5
It’s a remarkable study with some unexpected results — especially the relative importance of monounsaturated fatty acids (MUFAs) via the MUFA:SFA ratio, and yes, the positive performance of wine. But let’s not get into that here 
This study certainly doesn’t offer the holy grail for healthy ageing, nor a clear guide on what (or how much) to eat.
Any attempt to treat it that way is, in my view, misleading.
What it does show are dietary patterns that correlate with better ageing outcomes — not prescriptive rules.
In fact, many of the foods with log(OR) ≥ 0 are low in calories and would not sustain daily energy needs on their own. That’s precisely the point.
Certain foods — even in small quantities — can have disproportionate biological impact.
This supports the view that dietary quality is more relevant than quantity in promoting healthy ageing.
And importantly, the fact that many of these protective foods are not modern dietary staples opens the door for nutritional interventions — including targeted supplementation — to deliver the benefits of these patterns in a more accessible form.